Search results for "surface contamination"

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Environmental and Product Contamination during the Preparation of Antineoplastic Drugs with Robotic Systems

2018

Abstract Background Robotic systems are designed to minimize the exposure to antineoplastic drugs during automated preparation. However, contamination cannot be completely excluded. The aim of the study was to evaluate the contamination with antineoplastic drugs on the working surfaces and on the outer surface of the ready-to-use products (infusion bags and syringes) during automated preparation with different versions of a robot and manual preparation. Methods Surface contamination with platinum (Pt) and 5-fluorouracil (5-FU) was measured by wipe sampling and quantified by voltammetry for Pt and GC-MS for 5-FU. Sampling was performed on pre-defined locations in the working areas before and…

PharmacyRM1-950030226 pharmacology & pharmacygas chromatography/mass spectrometryantineoplastic drugs03 medical and health sciences0302 clinical medicineMedicinePharmacology (medical)Pharmaceutical industryPharmacologyvoltammetryChromatographybusiness.industrysurface contaminationautomated compoundingContaminationwipe samplingRobotic systems030220 oncology & carcinogenesisProduct (mathematics)Antineoplastic DrugsTherapeutics. PharmacologyGas chromatography–mass spectrometryHD9665-9675businessWipe samplingPharmaceutical Technology in Hospital Pharmacy
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